Adam Sandler
Christopher Walken
David Hasselhoff
Henry Winkler
Sean Astin
Jake Hoffman
Jennifer Coolidge

- Lauren Graham was offered the part of Donna Newman but declined the offer.
- Drew Barrymore was initially cast as Donna Newman but due to various reasons could not do the film.
- The little girl at the lakeside during young Michael's flashback is Kate Beckinsale's daughter, Lily Mo Sheen.
- The coin trick that Henry Winkler does in the movie is something he does in real life. During public appearances, he will often do the trick for children.
- At Ben's wedding in the future, the Freedom Tower can be seen in the NYC skyline (except there are two towers) where the World Trade Center once stood.
- As an in-joke, the names of some of the crew members are visible on a few headstones at the graveyard scene near the end of the film.

- Donna Newman: [scene after the dog humps toy duck] I have to sew the duck's head back on... and fix his butthole.
- Donna Newman: Will you still love me in the morning?
- Donna Newman: Forever and ever, babe.
- Donna Newman: I know it's deviant... but it's kinda turning me on.
- Donna Newman: Honey, you were so great.
- Donna Newman: Honey, what's going on down there?

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